YANGON, Myanmar (AP) -- The United Nations has confirmed that at least 48 Muslims appear to have been killed when Buddhist mobs attacked a village in an isolated corner of western Myanmar, violence that has been vehemently denied by the government since it was first reported by The Associated Press just over a week ago.
Presidential spokesman Ye Htut said he "strongly objects" to the U.N. claims and called its information and figures "totally wrong."
A statement issued Friday by Myanmar's Ministry of Foreign Affairs said accounts of the events issued by news organizations and international agencies were "based on unjustified conclusions drawing from unverified information," and would lead to misunderstandings among ethnic communities in the area.
It cautioned journalists and diplomats that "releasing unverified information" was tantamount to interfering in Myanmar's internal affairs.
The United States said it was "deeply disturbed" by the reports that at least 40 people have been killed, and that a police officer has disappeared. State Department spokeswoman Marie Harf called Friday for an immediate, independent investigation into the violence.
Myanmar, a predominantly Buddhist nation of 60 million people, has been grappling with sectarian violence since June 2012.
The incident in Du Chee Yar Tan, a village in northern Rakhine state, appears to be the deadliest in a year, and would bring the total number of mostly Muslims killed in violence nationwide to more than 280. Another 250,000 people have fled their homes.
Northern Rakhine -- home to 80 percent of the country's 1 million long-persecuted Muslim Rohingya population -- is off-limits to foreign journalists and humanitarian aid workers have limited access, adding to the difficulties of confirming details about the violence. Attacks began Jan. 9 and peaked in the early hours of Jan. 14, according to residents.
Buddhist Rakhine mobs, seeking retaliation for the abduction and killing of a police officer by Rohingya villagers, entered under the cloak of darkness with knives, sticks and guns and went on a killing spree, residents in the area told the AP on condition of anonymity because they feared reprisals. Many of the victims were women and children who were hacked to death by the mobs, they said.
The foreign ministry statement made no mention of vigilante attacks on Rohingya. It said police had two confrontations with mobs numbering 100 and 500 respectively, but caused no civilian injuries or deaths.
The humanitarian aid group Medecins Sans Frontieres, or Doctors Without Borders, said it has treated 22 patients, some with wounds. It appealed to the government for safe access to the affected people, many of whom are still in hiding.
Though the village has been sealed off by security forces, Matthew Smith of Fortify Rights, an independent human rights group, said some residents have been able to return during the day and, as of Wednesday, reported that some bodies were seen in abandoned homes. He called for an end to mass arrests, saying that in the hours that followed the killings, riot police started rounding up all male Rohingya, including children over the age of 10, in surrounding areas.
An investigation by the United Nations confirmed that a massacre had taken place. The U.N. released a statement late Thursday saying there were credible reports that at least 48 people had been killed in two separate bouts of violence.
The U.N. based its findings on interviews with witnesses, victims and local officials. But rights workers stressed that the full truth will only come out if the government authorizes a full investigation, preferably to be carried out with outside assistance.
"I deplore the loss of life in Du Chee Yar Tan and call on the authorities to carry out a full, prompt and impartial investigation and ensure that victims and their families receive justice," said Navi Pillay, the U.N. high commissioner for human rights.
"By responding to these incidents quickly and decisively, the government has an opportunity to show transparency and accountability, which will strengthen democracy and the rule of law in Myanmar," she said.
The first reports about the massacre occurred as Myanmar was hosting foreign ministers of the 10-member Association of Southeast Asian Nations as chair of the regional bloc.
It was supposed to be an event showing how far the country had come since ending a half-century of military dictatorship two years ago and handing over power to a nominally civilian government. The government of President Thein Sein, himself a former army general, has won international praise for implementing political and economic reforms, but it has also been criticized for failing to investigate and prosecute those responsible for killings linked to sectarian violence.